Young organs may not rejuvenate transplant recipients, study finds
Researchers at Brigham and Women's Hospital transplanted extra hearts into young and middle-aged mice and found the donor organ quickly adopted the recipient's biological age. Biopsies from human heart transplants showed the same pattern.
- Young hearts aged and old hearts rejuvenated inside the recipient
- Effect confirmed in decades of stored human heart biopsy samples
- Other organs and blood of the mice showed no changes after transplant
- Finding could expand use of hearts from older donors
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