Stem cell transplants restore movement in mice after stroke

Researchers at the University of Zurich transplanted human neural stem cells into mice one week after stroke. The cells survived five weeks, became neurons and reversed motor impairments, while also boosting blood vessel growth and reducing inflammation.

• Cells survived the full five-week study and connected with existing neurons
• Transplant one week after stroke worked better than immediate treatment
• Treatment improved blood vessels, cut inflammation and strengthened the blood-brain barrier
• Cells were derived from induced pluripotent stem cells without animal reagents