Scientists Find Brain Signal Tied to Ketamine's Antidepressant Effect

Researchers at Texas A&M analyzed EEG data from U.S. veterans over 55 after a single ketamine infusion: a larger increase in one measure of brain-wide information sharing at 24 hours was linked to greater symptom relief on day seven. The study was published in Translational Psychiatry.

• EEG was recorded 1 hour, 24 hours and 7 days after a single ketamine infusion
• Greater information-sharing at 24 hours correlated with symptom improvement on day 7
• The study involved U.S. veterans over 55 with treatment-resistant depression
• The brain changes could serve as a biomarker of treatment response