Scientists restore a brain protein and reverse signs of aging in mice

Scientists at Xiamen University showed that a decline in Menin protein in the hypothalamus is linked to aging: restoring it in 20-month-old mice improved memory, skin, and bones, while D-serine improved only cognitive functions. The work was published in PLOS Biology.

• Menin decline in hypothalamus caused bone weakness, skin thinning, memory loss in young mice
• Restoring protein in old mice over 30 days improved skin, bones, memory, balance
• D-serine in drinking water over 3 weeks improved only cognition, not physical aging
• Dietary L-serine from soy, eggs, fish does not replace experimental D-serine