Time-Restricted Eating Linked to Unexpected Changes in Huntington's Disease
A 12-week pilot study of 20 patients with early Huntington's disease found that eating within a 6-8 hour window was feasible without weight or muscle loss. Participants improved by 0.5 points on the cUHDRS scale, while blood levels of neurofilament light fell 13% and mitochondrial measures improved.
- 20 early-stage Huntington's patients ate within a 6-8 hour window for 12 weeks
- cUHDRS score improved by 0.5 points versus a typical 1-point yearly decline
- Blood neurofilament light levels fell by an average of 13%
- Body weight and lean muscle mass were maintained with few side effects
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