Nanoneedle arrays map RNA in fresh tissue without sequencing

Researchers developed nanoneedle arrays that spatially map RNA in fresh tissue without sequencing or amplification. The method reveals molecule locations across cells and microenvironments, with potential for routine clinical use in cancer, neurobiology and immunology.

• Nanoneedle arrays detect RNA directly in fresh tissue
• No sequencing or amplification required
• Method shows molecule locations across cells and tissues
• Approach targets routine clinical use