Freezing threatens mRNA delivery, but Tris buffer helps nanoparticles retain potency

Researchers at The University of Texas at Austin and Eli Lilly studied how storage conditions affect mRNA lipid nanoparticles (LNPs), the technology behind COVID-19 vaccines. Tris buffer helps the nanoparticles retain their potency during freezing.

• Study examined how storage conditions affect mRNA lipid nanoparticles
• Tris buffer preserves nanoparticle potency during freezing
• Project run by UT Austin and Eli Lilly