Single CAR T Injection Eases Multiple Sclerosis Symptoms in Small Trial

In a trial of 16 patients with autoimmune nervous system diseases, a single virus injection with genetic instructions created CAR-T cells directly in the body. No serious side effects occurred, and symptoms and molecular markers improved for over six months.

• 16 patients with multiple sclerosis and other autoimmune nervous system diseases
• Virus delivered instructions to reprogram T-cells in the body without extraction
• Symptoms and markers improved over 6 months, no severe complications
• Method may reduce cost of CAR-T therapy, which costs hundreds of thousands of dollars