DeepMind releases AlphaGenome Atlas: 9 billion DNA variants made public

Google DeepMind launched AlphaGenome Atlas, a free database covering 9 billion possible changes to the human genome with estimates of their effects on tissues and cellular processes. The 1-petabyte dataset is accessible through a web portal without bioinformatics expertise. Experts caution the model underestimates mutation effects and cannot always link regulatory elements to the genes they control.

• Database covers 9 billion DNA variants and totals 1 petabyte of data
• Accessible via web portal without API or bioinformatics skills
• AlphaGenome Variant Impact score separates disease-linked mutations from harmless ones
• Experts say the model underestimates effects and needs wet-lab validation