3-Year-Old Boy’s Cancer Disappears After He Gets Experimental Immunotherapy
A 3-year-old boy with metastatic hepatoblastoma achieved complete remission after experimental CAR-T therapy targeting the glypican-3 protein. The remission has lasted at least a year with no serious side effects. The results were published in the New England Journal of Medicine.
- Boy received two CAR-T infusions 8 weeks apart
- Remission persists at least 12 months without severe side effects
- Therapy targets glypican-3 protein and is enhanced with IL-15 and IL-21
- CARE trial plans to enroll 18–30 patients
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