Scientists Say Your Organs Don’t Grow Old Slowly—They Age in Two Sudden Bursts. Here’s When.

Scientists from Sanford Burnham Prebys and NIH developed the AI model PathStAR and analyzed 25,000 tissue images of 40 types from ~1,000 donors aged 21–70. Most organs age in two phases—accelerations occur around the 30s and 50s, linked to increased activity of inflammation genes.

• Analyzed 25,000 biopsy images of 40 tissue types
• Ovaries age rapidly at 35–40 and 55–60 years
• Vessels age only at 30–39, uterus and vagina around 50
• In most tissues, inflammation gene activity increases in both phases