Study: the brain is actually two separate organs, forebrain and hindbrain
Stanford researchers found that the brain forms from two distinct cell populations — forebrain and hindbrain — that split during gastrulation. The discovery could open new treatments for ALS and spinal muscular atrophy.
- Forebrain and hindbrain cells diverge within days of embryonic development
- The split is governed by chromatin and the genes Otx2 and Gbx2
- Hindbrain progenitors were grown in a lab for the first time
- The same pattern appears in mice, chickens, zebrafish and acorn worms
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