Glucosamine linked to faster Alzheimer's progression

University of Florida researchers analyzed health records from 2012–2024 and found glucosamine use was associated with a 25% higher likelihood that mild cognitive impairment would progress to dementia. Among patients with existing dementia, use was linked to a 25% higher mortality risk. The study was published in Nature Metabolism.

• Glucosamine use tied to 25% higher risk of MCI progressing to dementia
• In dementia patients, supplement use linked to 25% higher mortality risk
• Analysis covered 1,896 dementia patients and 2,750 with mild cognitive impairment
• Link tied to overactive protein glycosylation pathway in Alzheimer's brains